Tuberculose: Questões sobre Reinfecção Exógena e Reativação Endógena
DOI:
https://doi.org/10.5540/tema.2005.06.01.0121Abstract
Neste trabalho, formula-se um modelo matemático para descrever a dinâmica de transmissão da Tuberculose (TB) e avaliar os fatores de impacto na sua epidemia e no seu controle. Com a finalidade de abordar vários aspectos da epidemiologia da TB da forma mais simples possível considera-se que, uma vez infectado, o indíviduo pode progredir para a doença rapidamente (“fast” TB) ou de forma mais lenta, pela reativação endógena (“slow” TB), ou então, adquirir uma nova infecção, pela reinfecção exógena. Os efeitos da vacinação e do tratamento são também analisados como estratégias de controle. Nossos resultados sugerem que o aumento na taxa de incidência da TB é devido à reativação endógena (por exemplo, pela infecção pelo HIV) e/ou à reinfecção exógena.References
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